ea0063gp248 | Disturbances of Reproduction | ECE2019
Eyupoglu Damla
, Caliskan Guzelce Ezgi
, Acikgoz Aylin
, Uyanik Esra
, Bjorndal Bodil
, Berge Rolf
, Svardal Asbjorn
, Okan Yildiz Bulent
Context: Polycystic ovary syndrome (PCOS) is associated with an increased cardiometabolic risk that might not necessarily translate into adverse cardiovascular outcome later in life. Recently, alterations in gut microbial composition have been reported in the syndrome. Microbiota-dependent metabolite trimethylamine N-oxide (TMAO) and its precursors are closely linked with development of atherosclerotic cardiovascular disease, independently of traditional risk factors.<p cl...